Ultimate Nitric Oxide Nutrition FAQs

What are the side effects of taking Ultimate Nitric Oxide Nutrition?

There are no “side effects” per se. Most people just enjoy the health benefits of increasing their body’s innate power to produce nitric oxide. On very rare occasions, some may initially experience some digestive upset (loose bowels), which typically improves after a few days.

When should I take Ultimate Nitric Oxide Nutrition?

To maximize Ultimate Nitric Oxide Nutrition’s possibilities in activating your body’s innate power to realize optimum health, it is recommended to take Ultimate Nitric Oxide Nutrition separately from meals, at least one hour prior to or following.

Can I take Ultimate Nitric Oxide Nutrition if I am taking prescription medications?

It is always best to check with your doctor before adding something to your daily regimen. Ask your doctor: “Are there any contraindications for these nutrients?” That being said, Ultimate Nitric Oxide Nutrition has motivated wellness through daily use in thousands of individuals.

How much Ultimate Nitric Oxide Nutrition should I take?

The recommended dosage of Ultimate Nitric Oxide Nutrition for activating the body’s innate power to produce nitric oxide is two scoops per day.

How do I know if Ultimate Nitric Oxide Nutrition is working?

Many people will notice that their body is unlocking its innate potential first through better energy and sleep patterns, but the best results are usually seen over time. Allow for at least 3-6 months for your body to unlock its full potential.

Where are your l-arginine and l-citrulline sourced from? Do they contain pesticides or heavy metals?

We source our amino acids from a fermentation process conducted in South Korea that uses no heavy metals or pesticides. We also test the finished product for heavy metals and/or pesticides and herbicides (if of plant origin).

Is this product hard on the stomach?

Arginine has been known to be ‘hard on the stomach.’ However, Bionox uses arginine alpha-ketoglutarate and has digestive herbal support built in to minimize this tremendously. We have very, very few complaints about it causing digestive upset in our customers.

Is this a 100% natural product and made in the USA?

The product is 100% natural and manufactured in a FDA registered, GMP, US facility. We do not use artificial sweeteners or colors. It is flavored with berry juices.

How much arginine and citrulline is in Ultimate Nitric Oxide Nutrition?

There are over 5,000 mg of arginine and 2,000 mg of citrulline. The amounts of each are healthy doses and critical to ensuring longevity of nitric oxide levels.

What is the amount of oxalates per serving in your Nitric Oxide Nutrition?

All of our products contain zero oxalates.

What is the source of D3?

Sheep wool (lanolin)

Why does Bionox add so many antioxidants and premium herbal ingredients?

Nitric oxide (NO) is a highly reactive molecule that has a short half-life of a few seconds. As a result, it is susceptible to rapid degradation and inactivation by various reactive oxygen species (ROS) and other free radicals present in the body.

Antioxidants are compounds that help to neutralize ROS and other free radicals by donating an electron and thereby stabilizing the radical species. This is important because ROS and free radicals can react with NO and decrease its bioavailability, leading to reduced vasodilation, impaired endothelial function, and increased risk of cardiovascular disease.


Antioxidants can help to prolong the life of the NO molecule by neutralizing ROS and free radicals that would otherwise react with NO and impair its function. In addition, antioxidants can also help to regenerate other antioxidants that have been oxidized by ROS, such as glutathione, which can further protect NO from oxidative damage.


Several studies have shown that antioxidants can improve NO bioavailability and endothelial function. For example, a study published in the Journal of the American College of Cardiology found that administration of the antioxidant vitamin C improved endothelial function and increased NO bioavailability in patients with coronary artery disease. Another study published in the American Journal of Clinical Nutrition found that supplementation with the antioxidant alpha-tocopherol improved NO-mediated vasodilation in healthy adults.


Overall, antioxidants help to prolong the life of the NO molecule by neutralizing ROS and other free radicals that would otherwise react with NO and decrease its bioavailability. For these reasons we include the best antioxidants and herbs in our formula so that the nitric oxide molecule lasts much longer and absorbtion and arterial health is supported as well.

How long to see results for this product?

Energy increase is felt right away by most people. If you take the right dosage (1 scoop in the morning and 1 scoop 12 hours later. Most people see results within a few weeks. The best results are usually seen over time. Allow for at least 3-6 months for your body to unlock its full potential .

Where do the calories come from in M3 Nitric Oxide?

The calories come from the arginine, citrulline, and fruit juice powders.

Does UNON contain any amount of sugar? If so, how many grams does it have?

It has no sugar. It is sweetened with Stevia leaf extract.

What type of citrulline and arginine does this formula use?

L-Citruline (citrulline by itself, with nothing else attached). L-Arginine AKG (Arginine Alpha Ketoglutarate)

What is Nitric Oxide?

Nitric oxide is a gas molecule that is produced naturally within the body by the conversion of the amino acid L-arginine into nitric oxide by the enzyme nitric oxide synthase. It is a highly reactive molecule involved in various physiological processes within the body.

What will Nitric Oxide do for me?

It can help to lower blood pressure and improve cardiovascular health.

    • Enhanced exercise performance, including improved muscle contraction, reduced inflammation, and increased amino acid delivery to muscles.
    • Enhanced immune function, including the activation and coordination of immune responses, regulation of inflammation, and support for overall immune function and cardiovascular health.
    • Improved brain function, including regulation of blood flow to the brain, enhancement of neurotransmitter release, protection against oxidative stress and inflammation, and support for overall neurological health.
    • Improved sexual function, including regulation of blood flow to sexual organs, enhancement of erectile function in men, and support for sexual arousal and satisfaction in both men and women.

Why do I need Nitric Oxide?

Nitric Oxide is a molecule produced by nearly every cell in the human body. It is vital to numerous functions such as circulation, digestion, and energy production. is also responsible for intracellular communication, which is essential for cellular processes to be successful. A commonly accepted fact is that nitric oxide production naturally declines as we get older.

What are the "natural flavorings" used in Bionox products derived from?

The constituents of the “natural flavors” are proprietary to protect the intellectual property of Flavor Insights. We can share that only derivatives of the following ingredient categories fit within this scope:

“…a spice, fruit or fruit juice, vegetable or vegetable juice, edible yeast, herb, bark, bud, root, leaf or similar plant material, meat, seafood, poultry, eggs, dairy products, or fermentation products thereof, whose significant function in food is flavoring rather than nutritional.”

This is the FDA defined term for “natural flavors” that can be found in the CFR Title 21.


How does the mechanism of "Extended Release" work in a powder form?

Ultimate Nitric Oxide Nutrition, with its 2:1 ratio of arginine to citrulline along with vitamins and antioxidants, aims to support a more sustained release of nitric oxide (NO) in the body. Here's how the various components of the formula contribute to this goal:
  1. 2:1 ratio of arginine to citrulline: L-arginine is a direct precursor to nitric oxide and is readily converted to NO by the enzyme nitric oxide synthase (NOS). However, L-arginine is rapidly metabolized and has a relatively short half-life. L-citrulline, on the other hand, is converted to L-arginine in the body, thus providing a more sustained source of arginine for NO production. The 2:1 ratio ensures that there is an immediate release of NO from the arginine and a more sustained release as the citrulline is converted into arginine.
  2. Vitamins and antioxidants: Some vitamins, such as vitamin C and vitamin E, have antioxidant properties that help protect the NO molecule from being degraded by reactive oxygen species (ROS). By neutralizing these harmful free radicals, antioxidants can help maintain higher levels of NO in the body. Furthermore, certain vitamins, like vitamin D3 and vitamin K2, have been shown to support cardiovascular health, which may indirectly contribute to maintaining optimal NO levels.
  3. Synergistic action of ingredients: The combination of amino acids, vitamins, and antioxidants in Ultimate Nitric Oxide Nutrition works synergistically to support a more prolonged release of NO. While arginine and citrulline provide the raw materials for NO production, the vitamins and antioxidants help protect and maintain the NO molecule, allowing it to exert its vasodilatory effects over an extended period.

Is the xylitol used in your products sourced from birch or corn?

It is certified non-GMO corn.

Are the chlorella and cilantro grown in a controlled environment away from outside air?

Yes, both the chlorella and cilantro that we use are grown in a greenhouse.

Will nitric oxide supplements make me jittery?

Nitric oxide (NO) supplements themselves are not known to cause jitteriness. However, some products marketed as NO boosters may contain other ingredients, such as caffeine or stimulants, which can potentially lead to jitteriness or increased alertness. Bionox products don't contain those ingredients.

Why take nitric oxide on an empty stomach?

Taking nitric oxide (NO) supplements on an empty stomach is often recommended for better absorption and efficacy. Here's why:


Absorption: When taken on an empty stomach, NO supplements can be absorbed more quickly and efficiently. Without food in the stomach, the supplements can pass through the digestive system more rapidly, allowing for better absorption in the small intestine.


Avoiding competition for absorption: Some nutrients and compounds present in food, such as amino acids and dietary proteins, can compete with NO for absorption in the digestive system. By taking NO on an empty stomach, you minimize the potential interference from other substances, ensuring optimal absorption of the supplement.


Timing and effectiveness: Nitric oxide supplements are commonly used by athletes and individuals seeking improved exercise performance and increased blood flow. Taking them on an empty stomach, especially before a workout or physical activity, allows for quicker absorption and onset of action, potentially enhancing their effectiveness during exercise.


Minimizing digestive discomfort: Some individuals may experience mild digestive discomfort or bloating when taking NO supplements with food. Taking them on an empty stomach reduces the likelihood of these side effects.


However, it's important to note that the specific instructions for taking NO supplements may vary depending on the product and the manufacturer's recommendations. It's always advisable to follow the instructions provided on the product packaging or consult with a healthcare professional for personalized advice.