Muscular dystrophy is a group of genetic disorders characterized by progressive muscle weakness and degeneration. Nitric oxide (NO) is a molecule that plays an important role in various physiological processes, including blood flow, immune function, and muscle contraction.
Recent studies suggest that increasing levels of nitric oxide may have potential benefits for individuals with muscular dystrophy. One of the key ways that nitric oxide supports muscle function is by improving blood flow to muscles. This can help to increase oxygen and nutrient delivery, which can promote muscle growth and repair.
In addition, nitric oxide has been shown to have anti-inflammatory effects, which may help to reduce muscle damage and inflammation in individuals with muscular dystrophy. Furthermore, nitric oxide can improve mitochondrial function, which is essential for energy production in muscle cells.
1. "Nitric oxide is a therapeutic target for muscle dystrophy" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931422/) - This review article discusses the evidence supporting the use of NO as a therapeutic target for muscular dystrophy, including its effects on muscle regeneration, blood flow, and inflammation.
2. "Nitric oxide-mediated muscle regeneration in aging and muscular dystrophy" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768755/) - This study investigated the role of NO in muscle regeneration in both aging and muscular dystrophy. The authors found that NO plays an important role in promoting muscle stem cell proliferation and differentiation, and that NO supplementation can improve muscle regeneration in both conditions.
3. "Nitric oxide and skeletal muscle disease" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331574/) - This review article discusses the potential therapeutic applications of NO in various skeletal muscle diseases, including muscular dystrophy. The authors highlight the role of NO in promoting muscle regeneration and improving blood flow and oxygen delivery to the muscles.
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