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Arugula Super Cardio Greens

Supercharged with Arugula and 33 Amazing Whole Foods!

Arugula contains powerful, natural, and healthy nitrates - substances scientifically proven to boost nitric oxide and that offer incredible cardiovascular benefits. You deserve more from your Superfood - more energy, health benefits, and tangible results. Arugula Super Cardio Greens is a great-tasting, natural blend of 33 amazing whole foods that supports the heart, brain, vision, and immune system like no other health supplement available today.

 

 

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What is your superfood missing?

While some other superfoods contain vitamins and antioxidants that are good for you, most are missing a critical element; natural nitrates that work in tandem to boost health and blood flow. Modern farming methods have removed much of the healthy nitrates from our foods. This single deficiency is the root cause of multiple diseases of the cardiovascular and endocrine systems, the eyes, and the brain.


Nitric oxide brings more nutrients to the cells, making the Superfoods in our formula more powerful and absorbable. Nitric Oxide is the delivery system that efficiently and effectively delivers critically needed nutrients to the cells. Our Arugula Super Cardio Greens creates the nitric oxide the body needs and it contains the vital nutrients the cells need to operate at maximum efficiency.

What are natural nitrates?

Arugula can contain large amounts of natural nitrates when grown in suitable soil. These nitrates are responsible for producing and boosting nitric oxide levels in the human body. They have powerful cardiovascular and even immune system-boosting effects. These natural nitrates are unlike the synthetic ones found in processed meats like bacon, which should be avoided at all costs!

 

What is Nitric Oxide?

Nitric oxide is a gas produced in your body that makes your blood vessels open up and become more elastic. It has been used by bodybuilders to increase recovery time and strength and to pump up the muscles. It is also used in the medical world to help people with high blood pressure and heart disease.

 

Open, healthy veins and arteries bring more blood and nutrients to the organs and cells. Increased nitric oxide levels can bring remarkable, meaningful, and positive changes to one’s health. Boosting nitric oxide levels results in easy-to-spot results like more energy, more endurance, lower blood pressure, and overall health that the person feels day-to-day throughout each and every day.

33 Superfoods and Probiotics with 100 mg of Standardized Natural Arugula Nitrates.

The efficiency with which the human body absorbs and creates nitric oxide from arugula depends on gut health and probiotics in the mouth. Bacteria in the mouth are responsible for the conversion of nitrates into nitric oxide. The use of antibiotics and even mouthwash can raise blood pressure by many points due to this relationship! Kill the oral bacteria, and nitric oxide production stops dead in its tracks.
That's why we have included probiotics and stomach-friendly pro-gut superfoods in our Arugula Super Cardio Greens.
Heart and cognitive health depend on a healthy digestive system that can absorb and convert leafy greens into nitric oxide.

What makes Arugula Super Cardio Greens better than other formulas?

Other superfoods and greens products are focused on simply including the ingredients they know customers want to see on the label. It's like a party, and they want to invite everyone they can.

Arugula Super Cardio Greens is different because it uniquely adds a therapeutic dose of arugula along with 33 healthy whole foods. It's a VIP-only event!

 

Most other Superfood powders have no standardized nitrates or concentrated amounts of beneficial Superfoods, and there is no other product on the market today that offers the powerful combination of arugula and 33 whole foods. We stand alone in focusing on a therapeutic dose of one powerful ingredient and standardizing the dosage so it always works.

Other superfoods do not produce a feeling of well-being and energy. This product does.

Our customers who take Arugula Super Cardio Greens tell us they feel the positive effects immediately and consistently.

How to take Arugula Super Cardio Greens

This product can be taken as a stand-alone healthy supplement, or it can be combined with other Bionox products to create an even more powerful nitric oxide boost, along with all of the health benefits described above. It can be taken nonstop - no need to take breaks or cycle! One scoop of Arugula Super Cardio Greens can be taken for up to three times daily.

 

Where does this fit in with other Bionox products?

Arugula Super Cardio Greens is our Heart Healthy Superfood product.
• It can be taken with all of our other products.
• Take with our Bionox Ultimate Nitric Oxide Nutrition product for a 24-hour nitric oxide boost.
• Take with Chelanox to detox and bind unwanted toxins in the body.
• Take with Beetroot Energy for a nitric oxide boost on the go in easy-to-use cherry tarts.

 

 

I'm very happy with the taste

"I've tried many green superfood powders over the years but i never stay with it long term because of the taste. I decided to try Arugula Super Cardio Greens because I've been using Ultimate Nitric Oxide Nutrition for a couple of years and have seen an improvement in my blood pressure and over all circulatory health. I'm very happy with the taste, I'll have no problem staying with this product long term. Im very happy to be getting the nutrition from the super foods as well as a my Nitric Oxide boost from one powder. "

-Kyarb1

Love this stuff!

I love this stuff! I'm terrible at eating vegetables, so this is a game changer for me. The first time I tried them, I used the test strips. They were super easy to use, and I was surprised to see that the Arugula Super Cardio Greens worked so quickly. I mix it in grape juice, and after two days I couldn't even taste the powder anymore. I look forward to taking my greens every day.

-romancewriter

I feel the energy

I didn't think I would feel the difference when I started taking this but I have to say I am pleasantly surprised that I do feel the energy! It is a nice positive feeling that makes me feel good and I get a lot done in my day! The flavor is great as well! I add this to my collagen drink in the morning. Great to know I'm getting my greens daily!

-Debra Z. Fisher

Best Tasting Greens

I've purchased so many different green mixes, and this one is hands down the best I've tried. I do like things sweet, and I've been able to drink and enjoy this without just hurrying to choke it down.

-Mommy of four

Excellent way to increase NO in your blood.

I have a hereditary genetic defect where I do not produce Nitric Oxide (NO) from L-Arginine. So, I need to get most of my blood NO from metabolism of Nitrates or Nitrites. This is an excellent product, delivering a sustained amount of nitrates over night w/o a heavy carbohydrate hit. If the levels of NO in your blood is low, this is a great product to elevate it.

- Danny

 

I have seen a consistent drop in my high blood pressure

When my Doctor wanted to put on BP medication, I decided I wanted to try a more natural approach. Using Arugula Super Cardio Greens combined with Ultimate Nitric Oxide Nutrition I have seen a consistent drop in my high blood pressure with simply amazing results. Thank you Bionox!

-Vince A.

 



Arugula Super Cardio Greens FAQs

What is a superfood? Why are they so important?

A superfood is a nutrient-rich food considered to have very high nutritional density. This means they provide a lot of nutrients in a small amount of calories. Superfoods are good for you because they are high in vitamin and mineral content to help your body ward off health issues. They promote heart health, weight loss, energy levels, and can reduce the effects of aging when included in diets.

If there is no l-arginine or l-citrulline, how is this helping my body make nitric oxide?

Through the nitrate process. Nitrates are found in foods like spinach, arugula, and beets. Unfortunately, many foods lack the nitrate content they should have, so supplementing with products like Arugula Super Cardio Greens become critical.

How many nitrates are in each serving?

100 mg of nitrates per serving.

Is everything in this natural?

Yes, Arugula Super Cardio Greens includes 26 different superfoods, it alkalizes your system, there are naturally occurring vitamins through roots, fruits, spices, and vegetables, and it is naturally sweetened.

Should I take this with Ultimate Nitric Oxide Nutrition?

Yes, you absolutely can take this with Ultimate Nitric Oxide Nutrition. Both products focus on increasing your body's nitric oxide levels, while Arugula Super Cardio Greens gives you your daily dose of vegetables as well! Ultimate Nitric Oxide Nutrition increases your nitric oxide levels through the l-arginine/ l-citrulline method. Arugula Super Cardio Greens uses nitrates found in superfoods like arugula, spinach, and beets that convert to nitric oxide once consumed!

I used to buy Nox3 Greens. Is this the same product?

This is the exact same product. We have just updated the name and design!

Do you use organic greens? And are they verified?

The goal of Bionox Greens is to boost nitric oxide (NO) by using nitrate-rich ingredients. Unfortunately, most organic sources of these natural sources (arugula, spinach, beets, etc.) are very low in nitrates, so we have to use non-organic ingredients. However, the ingredients we use are extremely nutrient-rich.

Are Nitrates Bad for me?

Nitrates are compounds that can be naturally found in many vegetables and benefit human health. When nitrates from vegetables are consumed, they are converted into nitric oxide in the body, which can help to relax blood vessels, lower blood pressure, and improve blood flow. A study published in the American Journal of Clinical Nutrition found that a high-nitrate diet rich in leafy green vegetables was associated with significantly decreasing blood pressure in individuals with hypertension (Kapil et al., 2010).

While there is limited research specifically on the effects of nitrates on immune function, a study published in the Journal of Nutrition found that consumption of a high-nitrate diet improved immune function in older adults (Clifford et al., 2017). The study authors suggested that the beneficial effects may be due to the conversion of nitrates to nitric oxide, which can have anti-inflammatory effects.


On the other hand, nitrates added to processed meats such as bacon, ham, and hot dogs have been shown to increase the risk of certain diseases, including cancer. When nitrates are consumed in large amounts from processed meats, they can be converted into harmful compounds called nitrosamines. Nitrosamines are known to be carcinogenic, meaning they can increase the risk of cancer. A systematic review and meta-analysis published in the International Journal of Cancer found that consuming processed meats was associated with an increased risk of colorectal cancer. The risk increased with higher consumption of processed meats (Chan et al., 2011).

 
In summary, nitrates in vegetables can benefit human health when consumed, while nitrates in processed meats should be consumed cautiously to reduce the risk of harmful health effects.


References:

  • Kapil, V., Khambata, R. S., & Webb, A. J. (2010). The oral nitrate-nitrite pathway in hypertension and cardiovascular disease. American Journal of Clinical Nutrition, 90(3), 785S-788S.
  • Chan, D. S., Lau, R., Aune, D., Vieira, R., Greenwood, D. C., & Kampman, E. (2011). Red and processed meat and colorectal cancer incidence: meta-analysis of prospective studies. International Journal of Cancer, 128(6), 1411-1423.
  • World Health Organization. (2015). Q&A on the carcinogenicity of the consumption of red meat and processed meat. Retrieved from https://www.who.int/features/qa/cancer-red-meat/en/

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Nitric Oxide FAQ's

Why is nitric oxide so important?

Nitric oxide is essential since it allows blood, nutrients, and oxygen to travel to every part of your body. As we get older, our bodies' natural ability to make nitric oxide reduces, which increases the chances of unwanted health complications. By taking Bionox supplements, we can increase circulation, energy levels, digestion, muscle recovery, bones, sex, athletics, vitality, vision, and brain function.

Why do I need to be watching my nitric oxide levels?

As you get older, your body's ability to make nitric oxide decreases, opening you up to the risk of health challenges. By taking Bionox supplements, you are activating the innate power of your body to realize optimum health.

Is there really a need for a supplement?

Nitric Oxide supplements are overall safe to take. Each Bionox product serves a different purpose to help your body achieve optimum health..

What if I experience any negative symptoms?

All Bionox products are considered GRAS (Generally Regarded As Safe) compliant. However, as you use therapeutic doses of any nutrition, you may experience symptoms like digestive upset, fatigue, or others. Every person is unique and should be treated as such. Our general recommendation if you experience any unwanted effects based on perceived use of our products is to stop taking them for a few days and then try again slowly; such as taking half of the recommended dose or less and working up to the full dose if possible. If you still experience unwanted symptoms, you are welcome to get a full refund for your purchase.

Nitric oxide and muscular dystrohpy

Muscular dystrophy is a group of genetic disorders characterized by progressive muscle weakness and degeneration. Nitric oxide (NO) is a molecule that plays an important role in various physiological processes, including blood flow, immune function, and muscle contraction.

1. "Nitric oxide is a therapeutic target for muscle dystrophy" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931422/) - This review article discusses posible evidence supporting the use of NO as a therapeutic target for muscular dystrophy, including its effects on muscle regeneration, blood flow, and inflammation.

2. "Nitric oxide-mediated muscle regeneration in aging and muscular dystrophy" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768755/) - This study investigated the role of NO in muscle regeneration in both aging and muscular dystrophy. The authors found that NO plays an important role in promoting muscle stem cell proliferation and differentiation, and that NO supplementation may improve muscle regeneration in both conditions.

3. "Nitric oxide and skeletal muscle disease" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331574/) - This review article discusses the potential therapeutic applications of NO in various skeletal muscle diseases, including muscular dystrophy. The authors highlight the role of NO in promoting muscle regeneration and improving blood flow and oxygen delivery to the muscles.

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

Nitric oxide and glaucoma

Nitric oxide (NO) has been studied for its potential use in the treatment of glaucoma. Glaucoma is a group of eye diseases that can damage the optic nerve and cause vision loss or blindness. It is often associated with increased intraocular pressure (IOP) in the eye.

Nitric oxide is a molecule that is naturally produced in the body and has several functions, including the regulation of blood flow and the relaxation of smooth muscle. In the eye, NO is involved in regulating IOP and blood flow to the optic nerve.

Studies have shown that NO plays a role in regulating the tone of the trabecular meshwork, which is the tissue in the eye that helps to regulate the outflow of aqueous humor (the fluid in the eye). By increasing the outflow of aqueous humor, NO may help to lower IOP and reduce the risk of damage to the optic nerve.

In addition, NO may also have a neuroprotective effect on the optic nerve. Studies have suggested that NO may help to prevent or reduce damage to the optic nerve by increasing blood flow and reducing inflammation in the eye.

Several drugs that increase the production or availability of NO in the eye have been studied for their potential use in the treatment of glaucoma. These drugs include nitroglycerin, a drug used to treat angina, and sildenafil, a drug used to treat erectile dysfunction. Some studies have shown that these drugs can lower IOP and improve blood flow to the optic nerve in people with glaucoma.

Overall, while more research is needed, NO appears to have potential as a therapeutic target for the treatment of glaucoma. However, it is important to note that NO-based therapies are still in the experimental stage and should only be used under the guidance of a healthcare professional.

Here are some links to studies that explore the potential use of nitric oxide in the treatment of glaucoma:

1. "Nitric oxide as a mediator of intraocular pressure-independent retinal ganglion cell damage" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953946/)
This study looks at the role of nitric oxide in the damage to retinal ganglion cells in glaucoma.

2. "Nitric oxide and intraocular pressure" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148624/)
This study provides an overview of the role of nitric oxide in the regulation of intraocular pressure.

3. "Sildenafil Increases Ocular Blood Flow" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755073/)
This study investigates the effect of sildenafil on ocular blood flow in people with open-angle glaucoma.

4. "Nitroglycerin in glaucoma: a review" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831111/)
This review article summarizes the evidence for the use of nitroglycerin in the treatment of glaucoma.

5. "The effect of nitric oxide on ocular blood flow" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023972/)
This study looks at the effect of nitric oxide on ocular blood flow and intraocular pressure in healthy volunteers.

Please note that these studies are not exhaustive, and there may be more recent or relevant studies available.


*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

Nitric oxide and diabetes

Research has suggested that nitric oxide (NO) plays a crucial role in the development and progression of diabetes.
One study found that NO production was significantly reduced in individuals with type 2 diabetes compared to healthy individuals. This reduction in NO production is believed to contribute to impaired blood vessel function and the development of cardiovascular complications in diabetes.

Another study found that increasing NO levels in individuals with type 2 diabetes improved their insulin sensitivity and glucose metabolism.
Furthermore, research has shown that NO plays a role in regulating insulin secretion from pancreatic beta cells, which are responsible for producing insulin in the body. Impaired NO production may contribute to the dysfunction of beta cells and the development of diabetes.

Overall, the research suggests that maintaining healthy levels of NO may be important in preventing and managing diabetes. However, more research is needed to fully understand the relationship between NO and diabetes and how NO-based therapies could be used to treat diabetes.

1. "Nitric oxide and diabetic nephropathy" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725516/)

2. "The Role of Nitric Oxide in Insulin Secretion" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432264/)

3. "Nitric oxide in the pathogenesis and treatment of diabetic vascular disease" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963062/)

4. "The Role of Nitric Oxide in the Development of Cardiovascular Complications of Diabetes" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428723/)

5. "Effect of Nitric Oxide on Glucose Metabolism and Insulin Sensitivity" (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554244/)

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

Nitric oxide and the immune system

Study Title: "Nitric oxide in the immune system: a historical overview" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248324/)
Summary: This review article provides an overview of the role of nitric oxide (NO) in the immune system. The authors discuss the various ways in which NO is produced by immune cells and its diverse effects on the immune response. They also highlight the potential therapeutic applications of NO in the treatment of various immune-related disorders.

Study Title: "Regulation of immune cell function by nitric oxide" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266519/)
Summary: This review article focuses on the regulation of immune cell function by NO. The authors discuss the effects of NO on various immune cells, including macrophages, dendritic cells, T cells, and B cells. They also highlight the potential therapeutic applications of NO in the treatment of various immune-related disorders.

Study Title: "Nitric oxide regulates immunity against infections by promoting Type I IFN production" (Link: https://www.nature.com/articles/s41467-021-24081-4)
Summary: This study investigates the role of NO in the immune response to SARS infection. The authors show that NO promotes the production of type I interferons (IFNs), which play a critical role in the antiviral response to SARS. They also show that NO can enhance the efficacy of antiviral therapies in mice infected with SARS.

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.


What do studies say about l-arginine supplementation?

Study Title: "L-arginine and Cardiovascular Diseases: From Molecular Mechanisms to Therapeutic Implications" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360456/)

Summary: This review article discusses the molecular mechanisms by which L-arginine supplementation may benefit cardiovascular health. The authors highlight the potential role of L-arginine in improving endothelial function, reducing inflammation, and lowering blood pressure.

 

Study Title: "L-arginine and heart failure" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842162/)

Summary: This review article discusses the potential benefits of L-arginine supplementation in patients with heart failure. The authors highlight the potential role of L-arginine in improving endothelial function, reducing inflammation, and enhancing exercise capacity.

 

Study Title: "Effects of L-arginine supplementation on blood pressure: a meta-analysis of randomized controlled trials" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573572/)

Summary: This meta-analysis of randomized controlled trials evaluates the effects of L-arginine supplementation on blood pressure. The authors found that L-arginine supplementation significantly reduced both systolic and diastolic blood pressure.

 

Study Title: "Effects of long-term oral L-arginine on the nitric oxide synthase pathway in the urine from patients with coronary artery disease" (Link: https://pubmed.ncbi.nlm.nih.gov/22227316/)

Summary: This study investigates the effects of long-term L-arginine supplementation on the nitric oxide synthase pathway in patients with coronary artery disease. The authors found that L-arginine supplementation increased nitric oxide production and improved endothelial function in these patients.

 

Study Title: "L-Arginine in the management of cardiovascular diseases" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753343/)

Summary: This review article discusses the potential benefits of L-arginine supplementation in the management of cardiovascular diseases, including hypertension, heart failure, and atherosclerosis. The authors highlight the potential role of L-arginine in improving endothelial function, reducing oxidative stress, and enhancing nitric oxide production.

 
 
*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

What do studies on hawthorn berry say?

Study Title: "The cardiovascular pharmacotherapy of hawthorn extract in comparison to usual therapies for cardiovascular disease: a systematic review and meta-analysis" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634761/)

Summary: This systematic review and meta-analysis evaluated the cardiovascular pharmacotherapy of Hawthorn extract. The authors found that Hawthorn extract was effective in reducing blood pressure, improving lipid profile, and enhancing endothelial function, without any significant adverse effects.

 

Study Title: "Effects of hawthorn extract supplementation on cardiovascular risk factors in Korean men and women" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137437/)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of Hawthorn extract supplementation on cardiovascular risk factors in Korean men and women. The authors found that Hawthorn extract supplementation significantly improved blood pressure, lipid profile, and endothelial function in the study participants.

 

Study Title: "Hawthorn (Crataegus spp.) in the treatment of cardiovascular disease" (Link: https://pubmed.ncbi.nlm.nih.gov/15886464/)

Summary: This review article provides an overview of the potential cardiovascular benefits of Hawthorn. The authors discuss the various ways in which Hawthorn can improve cardiovascular health, including its antioxidant, anti-inflammatory, and anti-atherogenic effects.

 

Study Title: "Effectiveness and safety of a herbal drug containing hawthorn berries and D-camphor in hypotension and orthostatic circulatory disorders/results of a retrospective epidemiologic cohort study" (Link: https://pubmed.ncbi.nlm.nih.gov/11995906/)

Summary: This retrospective epidemiologic cohort study investigated the effectiveness and safety of a herbal drug containing Hawthorn berries and D-camphor in hypotension and orthostatic circulatory disorders. The authors found that the herbal drug was effective in improving symptoms of hypotension and orthostatic circulatory disorders, with no significant adverse effects.

 

Study Title: "The effect of hawthorn (Crataegus oxycantha) extract on cardiovascular risk factors in type 2 diabetes mellitus: a randomized controlled trial" (Link: https://pubmed.ncbi.nlm.nih.gov/22494792/)

Summary: This randomized controlled trial investigated the effects of Hawthorn extract on cardiovascular risk factors in type 2 diabetes mellitus. The authors found that Hawthorn extract supplementation significantly improved blood pressure, lipid profile, and glycemic control in the study participants.

 

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

What studies are there on green coffee bean extract?

Green coffee bean extract (GCBE) is a supplement that is derived from unroasted coffee beans. It is often promoted for its potential health benefits, including its cardioprotective effects. Here are three studies that provide evidence for GCBE's potential cardioprotective properties:

 

Study Title: "Green coffee bean extract improves cardiometabolic parameters and vascular function in obese, hypertensive subjects" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943088/)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of GCBE supplementation on cardiometabolic parameters and vascular function in obese, hypertensive subjects. The authors found that GCBE supplementation improved several markers of cardiovascular health, including blood pressure, endothelial function, and oxidative stress.

 

Study Title: "Green coffee extract supplementation improves cardiovascular risk biomarkers in obese women" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082221/)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of GCBE supplementation on cardiovascular risk biomarkers in obese women. The authors found that GCBE supplementation improved several markers of cardiovascular health, including blood pressure, lipid profile, and inflammatory markers.

 

Study Title: "Effect of green coffee extract on cardiovascular health: evidence from preclinical and clinical studies" (Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647072/)

Summary: This review article provides an overview of the preclinical and clinical evidence supporting the cardioprotective effects of GCBE. The authors discuss the various mechanisms by which GCBE may improve cardiovascular health, including its antioxidant and anti-inflammatory properties, as well as its ability to improve lipid metabolism and blood pressure regulation. They also highlight several clinical studies that have reported improvements in cardiovascular risk factors with GCBE supplementation.

 

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

What studies have been done on Vitamin D and nitric oxide?

Study Title: "Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels" (Link: https://pubmed.ncbi.nlm.nih.gov/22923665/)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of Vitamin D supplementation on endothelial function in patients with Type 2 diabetes mellitus and low Vitamin D levels. The authors found that Vitamin D supplementation improved endothelial function, as measured by flow-mediated dilation, which is related to increased nitric oxide production.

 

Study Title: "Vitamin D and endothelial function" (Link: https://pubmed.ncbi.nlm.nih.gov/24413322/)

Summary: This review article discusses the potential role of Vitamin D in improving endothelial function, which is mediated in part by increased nitric oxide production. The authors highlight the various mechanisms by which Vitamin D can influence nitric oxide production and improve endothelial function, including through regulation of gene expression and calcium homeostasis.

 

Study Title: "Vitamin D deficiency and risk of cardiovascular disease" (Link: https://pubmed.ncbi.nlm.nih.gov/28578227/)

Summary: This review article discusses the potential link between Vitamin D deficiency and increased risk of cardiovascular disease. The authors highlight the various ways in which Vitamin D can influence cardiovascular health, including its role in improving endothelial function and nitric oxide production. They also discuss the potential mechanisms by which Vitamin D deficiency can contribute to cardiovascular disease, such as through increased inflammation and oxidative stress.

 

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

What studies have been done on Vitamin E and nitric oxide?

Study Title: "Vitamin E enhances endothelial nitric oxide synthase activity in endothelial cells" (Link: https://www.ncbi.nlm.nih.gov/pubmed/9856938)

Summary: This study investigated the effect of vitamin E on endothelial nitric oxide synthase (eNOS) activity in endothelial cells. The authors found that treatment with vitamin E increased eNOS activity and nitric oxide production, suggesting that vitamin E may enhance endothelial function by promoting nitric oxide production.

 

Study Title: "Vitamin E supplementation improves endothelial function in type 1 diabetes mellitus: a randomized, placebo-controlled study" (Link: https://www.ncbi.nlm.nih.gov/pubmed/19109500)

Summary: This randomized, placebo-controlled study investigated the effect of vitamin E supplementation on endothelial function in patients with type 1 diabetes mellitus. The authors found that vitamin E supplementation improved endothelial function, as measured by flow-mediated dilation of the brachial artery, suggesting that vitamin E may help to improve nitric oxide bioavailability and promote cardiovascular health in patients with diabetes.

 

Study Title: "Vitamin E and nitric oxide in pre-eclampsia: another example of endothelial dysfunction?" (Link: https://www.ncbi.nlm.nih.gov/pubmed/11466662)

Summary: This study investigated the relationship between vitamin E and nitric oxide in women with pre-eclampsia, a condition characterized by endothelial dysfunction. The authors found that women with pre-eclampsia had lower levels of nitric oxide and vitamin E compared to healthy controls, suggesting that vitamin E may play a role in promoting nitric oxide production and endothelial function in this population.

 

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

What do studies say about grape seed extract?

Grape seed extract (GSE) is a dietary supplement that is often promoted for its potential health benefits, including its cardioprotective effects. Here are three studies that provide evidence for GSE's potential heart health benefits:

 

Study Title: "Grape seed extract reduces blood pressure in hypertensive subjects" (Link: https://www.ncbi.nlm.nih.gov/pubmed/15640470)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of GSE supplementation on blood pressure in hypertensive subjects. The authors found that GSE supplementation significantly reduced systolic blood pressure compared to placebo, suggesting that GSE may have antihypertensive effects and may help to improve cardiovascular health.

 

Study Title: "Effects of grape seed extract consumption on platelet function and blood pressure in hypertensive subjects" (Link: https://www.ncbi.nlm.nih.gov/pubmed/24334460)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of GSE supplementation on platelet function and blood pressure in hypertensive subjects. The authors found that GSE supplementation improved platelet function and reduced systolic blood pressure compared to placebo, suggesting that GSE may have beneficial effects on both hemostasis and cardiovascular health.

 

Study Title: "Grape seed extract supplementation attenuates the adverse effects of high-fat diet on endothelial function in rats" (Link: https://www.ncbi.nlm.nih.gov/pubmed/19284627)

Summary: This animal study investigated the effects of GSE supplementation on endothelial function in rats fed a high-fat diet. The authors found that GSE supplementation improved endothelial function, as measured by aortic relaxation responses, and reduced oxidative stress and inflammation in the aorta, suggesting that GSE may have cardioprotective effects by improving endothelial function and reducing oxidative stress.

 

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.

What do studies say about beetroot extract?

Beetroot extract has gained attention for its potential benefits for cardiovascular health, particularly in the context of exercise and blood pressure. Here are five studies that investigate the effects of beetroot extract on blood pressure and exercise:

 

Study Title: "Beetroot juice and exercise: pharmacodynamic and dose-response relationships" (Link: https://www.ncbi.nlm.nih.gov/pubmed/23839191)

Summary: This study investigated the dose-response relationship between beetroot juice supplementation and exercise performance and blood pressure in healthy adults. The authors found that higher doses of beetroot juice led to greater improvements in exercise performance and blood pressure, suggesting that beetroot juice may have potential as an ergogenic aid and blood pressure-lowering agent.

 

Study Title: "Effect of beetroot juice on lowering blood pressure in free-living, disease-free adults: a randomized, placebo-controlled trial" (Link: https://www.ncbi.nlm.nih.gov/pubmed/23473470)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of beetroot juice supplementation on blood pressure in healthy adults. The authors found that beetroot juice supplementation significantly reduced systolic blood pressure compared to placebo, suggesting that beetroot juice may have potential as a dietary intervention for reducing blood pressure.

 

Study Title: "Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players" (Link: https://www.ncbi.nlm.nih.gov/pubmed/23842842)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of beetroot juice supplementation on high-intensity intermittent exercise performance in trained soccer players. The authors found that beetroot juice supplementation improved exercise performance and reduced perceived exertion compared to placebo, suggesting that beetroot juice may have potential as an ergogenic aid for athletes.

 

Study Title: "Acute effect of a high nitrate diet on brain perfusion in older adults" (Link: https://www.ncbi.nlm.nih.gov/pubmed/25459980)

Summary: This study investigated the effects of a high-nitrate diet, which included beetroot juice, on brain perfusion in older adults. The authors found that the high-nitrate diet improved cerebral blood flow in several regions of the brain, suggesting that beetroot juice may have potential as a dietary intervention for promoting brain health.

 

Study Title: "Acute beetroot juice supplementation on sympathetic nerve activity: a randomized, double-blind, placebo-controlled proof-of-concept study" (Link: https://www.ncbi.nlm.nih.gov/pubmed/27716697)

Summary: This randomized, double-blind, placebo-controlled trial investigated the effects of beetroot juice supplementation on sympathetic nerve activity in healthy adults. The authors found that beetroot juice supplementation reduced sympathetic nerve activity, which is associated with cardiovascular disease risk, suggesting that beetroot juice may have potential as a dietary intervention for reducing cardiovascular disease risk.

 

*These statements have not been evaluated by the Food and Drug Administration. This product or any product on our website is not intended to diagnose, treat, cure or prevent any disease.



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