All of our products contain zero oxalates.

Sheep wool (lanolin)

Nitric oxide (NO) is a highly reactive molecule that has a short half-life of a few seconds. As a result, it is susceptible to rapid degradation and inactivation by various reactive oxygen species (ROS) and other free radicals present in the body.

Antioxidants are compounds that help to neutralize ROS and other free radicals by donating an electron and thereby stabilizing the radical species. This is important because ROS and free radicals can react with NO and decrease its bioavailability, leading to reduced vasodilation, impaired endothelial function, and increased risk of cardiovascular disease.

Antioxidants can help to prolong the life of the NO molecule by neutralizing ROS and free radicals that would otherwise react with NO and impair its function. In addition, antioxidants can also help to regenerate other antioxidants that have been oxidized by ROS, such as glutathione, which can further protect NO from oxidative damage.

Several studies have shown that antioxidants can improve NO bioavailability and endothelial function. For example, a study published in the Journal of the American College of Cardiology found that administration of the antioxidant vitamin C improved endothelial function and increased NO bioavailability in patients with coronary artery disease. Another study published in the American Journal of Clinical Nutrition found that supplementation with the antioxidant alpha-tocopherol improved NO-mediated vasodilation in healthy adults.

Overall, antioxidants help to prolong the life of the NO molecule by neutralizing ROS and other free radicals that would otherwise react with NO and decrease its bioavailability. For these reasons we include the best antioxidants and herbs in our formula so that the nitric oxide molecule lasts much longer and absorbtion and arterial health is supported as well.

The calories come from the arginine, citrulline, and fruit juice powders.

It has no sugar. It is sweetened with Stevia leaf extract.

L-Citruline (citrulline by itself, with nothing else attached). L-Arginine AKG (Arginine Alpha Ketoglutarate)

Nitric oxide is a gas molecule that is produced naturally within the body by the conversion of the amino acid L-arginine into nitric oxide by the enzyme nitric oxide synthase. It is a highly reactive molecule involved in various physiological processes within the body.

It can help to lower blood pressure and improve cardiovascular health.

• • Enhanced exercise performance, including improved muscle contraction, reduced inflammation, and increased amino acid delivery to muscles.
  • Enhanced immune function, including the activation and coordination of immune responses, regulation of inflammation, and support for overall immune function and cardiovascular health.
  • Improved brain function, including regulation of blood flow to the brain, enhancement of neurotransmitter release, protection against oxidative stress and inflammation, and support for overall neurological health.
  • Improved sexual function, including regulation of blood flow to sexual organs, enhancement of erectile function in men, and support for sexual arousal and satisfaction in both men and women.

Nitric Oxide is a molecule produced by nearly every cell in the human body. It is vital to numerous functions such as circulation, digestion, and energy production. is also responsible for intracellular communication, which is essential for cellular processes to be successful. A commonly accepted fact is that nitric oxide production naturally declines as we get older.

1. 2:1 ratio of arginine to citrulline: L-arginine is a direct precursor to nitric oxide and is readily converted to NO by the enzyme nitric oxide synthase (NOS). However, L-arginine is rapidly metabolized and has a relatively short half-life. L-citrulline, on the other hand, is converted to L-arginine in the body, thus providing a more sustained source of arginine for NO production. The 2:1 ratio ensures that there is an immediate release of NO from the arginine and a more sustained release as the citrulline is converted into arginine.
2. Vitamins and antioxidants: Some vitamins, such as vitamin C and vitamin E, have antioxidant properties that help protect the NO molecule from being degraded by reactive oxygen species (ROS). By neutralizing these harmful free radicals, antioxidants can help maintain higher levels of NO in the body. Furthermore, certain vitamins, like vitamin D3 and vitamin K2, have been shown to support cardiovascular health, which may indirectly contribute to maintaining optimal NO levels.
3. Synergistic action of ingredients: The combination of amino acids, vitamins, and antioxidants in Ultimate Nitric Oxide Nutrition works synergistically to support a more prolonged release of NO. While arginine and citrulline provide the raw materials for NO production, the vitamins and antioxidants help protect and maintain the NO molecule, allowing it to exert its vasodilatory effects over an extended period.

Yes, both the chlorella and cilantro that we use are grown in a greenhouse.

Nitric oxide (NO) supplements themselves are not known to cause jitteriness. However, some products marketed as NO boosters may contain other ingredients, such as caffeine or stimulants, which can potentially lead to jitteriness or increased alertness. Bionox products don't contain those ingredients.

Taking nitric oxide (NO) supplements on an empty stomach is often recommended for better absorption and efficacy. Here's why:

Absorption: When taken on an empty stomach, NO supplements can be absorbed more quickly and efficiently. Without food in the stomach, the supplements can pass through the digestive system more rapidly, allowing for better absorption in the small intestine.

Avoiding competition for absorption: Some nutrients and compounds present in food, such as amino acids and dietary proteins, can compete with NO for absorption in the digestive system. By taking NO on an empty stomach, you minimize the potential interference from other substances, ensuring optimal absorption of the supplement.

Timing and effectiveness: Nitric oxide supplements are commonly used by athletes and individuals seeking improved exercise performance and increased blood flow. Taking them on an empty stomach, especially before a workout or physical activity, allows for quicker absorption and onset of action, potentially enhancing their effectiveness during exercise.

Minimizing digestive discomfort: Some individuals may experience mild digestive discomfort or bloating when taking NO supplements with food. Taking them on an empty stomach reduces the likelihood of these side effects.

However, it's important to note that the specific instructions for taking NO supplements may vary depending on the product and the manufacturer's recommendations. It's always advisable to follow the instructions provided on the product packaging or consult with a healthcare professional for personalized advice.

AstraGin® is a patented blend of highly purified saponins isolated from the Astragalus membranaceus and Panax notoginseng plant. It enhances the absorption of various nutrients including amino acids like L-Arginine and L-Citrulline, ensuring optimal availability for NO production.

As the UNON goes to work healing the endothelium it's possible that it will "kick out" metals as it heals.

Our products are oxalate free.

The content of caffeine is around 1% of the total weight of unroasted coffee. So 50mg of green coffee bean (which is what is in a serving of UNON) is going to have 5mg (one-half milligram) maximum (not even one mg) of caffeine. For reference, an average 12 oz cup of coffee contains about 95-165 mg of caffeine, so, one serving in a glass of water will at most have 1mg of caffeine. It's not even a milligram.

As long as no other competing amino acids are taken, you will be 100% fine. You can take it with anything that is carbohydrate only. So, veggies are fine. What will stop the absorption is protein. And, it's not that it won't work or will hurt anything, it’s that it won’t work as well if you take it with protein-based foods

Nitric oxide (NO) has been studied for its potential role in treating bleeding ulcers. NO is a molecule that naturally occurs in the body and plays various roles, including regulating blood flow and protecting the gastric mucosa (lining of the stomach).

In the context of bleeding ulcers, NO has been found to have several potential benefits. It helps to dilate blood vessels in the mucosal lining, increasing blood flow and promoting healing. NO also helps to inhibit the growth of certain bacteria, such as Helicobacter pylori, which is often associated with ulcer development.

Additionally, NO can help suppress inflammation in the stomach, which is a common occurrence in ulcer cases. It works by reducing the production of pro-inflammatory molecules, thereby potentially reducing the severity of ulcers and preventing bleeding.

That being said, it's important to note that the use of NO in the treatment of bleeding ulcers is still being researched.

No, we don't.

It is grown in China.

The Beetroot Energy does the same thing as the Ultimate Nitric Oxide; it's just via a different mechanism. Beetroot Energy uses nitrates to boost nitric oxide, whereas Ultimate Nitric Oxide Powder uses arginine, citrulline, herbs, and vitamin D.

Ultimate Nitric Oxide nutrition will not take you out of ketosis. It has almost zero sugar, less than 2 grams.

Our products are 100% safe; however, it is important to talk with a physician before taking any dietary supplement. Ultimate Nitric Oxide Nutrition is our #1 product, preferred by athletes across the country